Randomized controlled study of efficacy and safety of drotaverine hydrochloride in patients with irritable bowel syndrome

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Randomized controlled study of efficacy and safety of drotaverine hydrochloride in patients with irritable bowel syndrome

BACKGROUND This study aimed to assess the efficacy and safety of drotaverine hydrochloride (DHC) in Chinese patients with irritable bowel syndrome (IBS). METHODS Totally, 144 patients with IBS were included and randomly divided into treatment group and placebo group in a 1:1 ratio. Patients received either DHC or placebo 80-mg tablet, 3 times daily for a total of 4 weeks. The primary outcome ...

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randomized controlled trial study about compare of post operative pain after milligan morgan versus submucosal hemorrhoidectomy with & without pudendal nerve marcaine block in patients that had hemorrhoidectomy in imam hossein hospital of shahrood in 1389-90

مقدمه:هموروئید یکی از شایعترین بیماریهای جراحی ناحیه آنورکتال است که با درد و خونریزی بروز می کند. کاهش دردبعد عمل علاوه بر افزایش رضایت بیمار باعث کاهش مدت بستری و کاهش بار تحمیلی بر روی اقتصاد جامعه می گردد. مطالعه حاضر مقایسه ای از لحاظ میزان درد و میزان تأثیر مارکائین به عنوان روشی برای پروفیلاکسی درد بعداز عمل،دو روش هموروئیدکتومی باز و بسته انجام می دهد. مواد وروشها: این مطالعه کارآزمایی...

Seroprevalence of Campylobacter Jejuni in Patients with Irritable Bowel Syndrome and in Healthy Individuals

Abstract Background and Objective: The patients with Post-Infectious Irritable bowel syndrome (PI-IBS), a subtype of irritable bowel syndrome, suffer from bacterial gastroenteritis. Since campylobacter Jejuni (CJ) is one of the most common agents in this syndrome, we aimed to evaluate the prevalence of Campylobacter Jejuni in patients with Irritable Bowel Disease. Material and Methods: Th...

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Efficacy and Safety of Drotaverine Hydrochloride in Children with Recurrent Abdominal Pain: A Randomized Placebo Controlled Trial.

OBJECTIVE To evaluate the efficacy and safety of Drotaverine hydrochroride in children with recurrent abdominal pain. DESIGN Double blind, randomized placebo-controlled trial. SETTING Pediatric Gastroenterology clinic of a teaching hospital. PARTICIPANTS 132 children (age 4-12 y) with recurrent abdominal pain (Apley Criteria) randomized to receivedrotaverine (n=66) or placebo (n=66) orall...

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A Randomized Clinical Trial of Berberine Hydrochloride in Patients with Diarrhea-Predominant Irritable Bowel Syndrome.

We aimed to evaluate clinical symptoms in diarrhea predominant irritable bowel syndrome (IBS-D) receiving berberine hydrochloride in a randomized double-blind placebo-controlled clinical trial. Overall, 196 patients with IBS-D were recruited for this study; consequently, 132 patients randomized to receive daily 400 mg of berberine hydrochloride, delivered twice daily or placebo for 8 weeks foll...

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ژورنال

عنوان ژورنال: Medicine

سال: 2017

ISSN: 0025-7974

DOI: 10.1097/md.0000000000009235